Lipidomic Characterization of Body Fluids and Tissues for Patients Suffering from Serious Diseases Using Mass Spectrometry

Postdoc researcher will participate in the development and introduction of new methods in the lipidomic characterization of body fluids and tissues for patients suffering from serious human diseases, such as cardiovascular diseases, various types of cancer or Alzheimer disease. The lipidomic characterization includes all analytical steps starting from the preparation of biological samples (plasma, surgically removed cancer tissues and other types of samples), the preparative fractionation of individual lipid classes and finally detailed characterization using one or multidimensional liquid chromatography coupled to mass spectrometry. The lipidomic quantitation will be performed for large number of lipids followed by the multivariate statistical evaluation (PCA, PLS, etc.) with the goal to find biomarkers for individual types of studied diseases.

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Mass Spectrometry Imaging of Biological Tissues

Postdoc researcher will participate in the development of new methods for mass spectrometry imaging using matrix-assisted laser desorption/ionization (MALDI) and other related desorption ionization techniques (e.g., LDI, NALDI, DESI). Individual analytical steps will be carefully optimized, mainly the sample preparation, the way of matrix introduction (spraying vs. sublimation procedures), the type of matrix and finally the parameters of mass spectrometric measurements. Mass spectrometry imaging will be applied especially for the analysis of drugs and their metabolites in animal tissues and for the spatial imaging of lipid distribution in patient and animal tissues.

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Cancer Research Center (DKFZ) in Heidelberg, Germany Doctoral position avaliable

The Helmholtz International Graduate School for Cancer Research is an interdisciplinary PhD program, providing students with the opportunity to conduct research at the forefront of basic and translational cancer research in a dynamic work environment with access to state-of-the-art research facilities, experienced supervisors and exceptional resources.

PhD projects are available in the following research areas:

a. Cell Biology and Tumor Biology

b. Structural and Functional

c. Cancer Risk Factors and Prevention

d. Tumor Immunology

e. Imaging and Radiooncology

f. Infection and Cancer

g. Translational Cancer Research

The next deadline for PhD applications is 5th January 2012 and shortlisted candidates will be invited to attend a 3-day interview at the DKFZ at the end of February 2012.

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PhD POSITIONS in Europe

Eligible applicants have not yet been awarded a doctoral degree and are in the first four years (full-time equivalent) of their research careers. This includes the period of research training, starting at the date of obtaining the degree which would formally entitle the eligible candidate to embark on a doctorate either in the country in which the degree was obtained or in the country of the host organisation. Additionally, at the time of recruitment by the host organisation the successful candidate must not have resided or carried out his/her main activity (work, studies, etc) in the country of the host organisation for more than 12 months in the 3 years immediately prior to his/her recruitment. Compulsory national service and/or short stays such as holidays are not taken into account.

Your application should consist of

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Doctoral positions at the Department of Law from 1 September 2012.

A requirement for employment as doctoral student is that the applicant must be admitted to postgraduate studies. To this extent, the applicant’s ability to successfully complete the doctoral studies will be decisive. The regulations governing the employment of doctoral students may be found in Chapter 5, §§ 1-7 of the Higher Education Ordinance.

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PhD student positions in mathematics

The duties of a PhD student are primarily directed at his/her own research education, which lasts 4 years. The job may also involve to a limited extent (maximum 20 %) other departmental duties, mainly related to teaching undergraduate courses - in which case the position may be extended to maximum 5 years. The salary level is set by the university regulations. During the first year of studies the principle of 80 % study grant and 20 % assistantship is applied.

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Manganese chemistry (Inorganic Chemistry) postdoctoral position

We seek a PhD graduate with some experience in the synthesis and characterisation of new molecular magnetic materials. An excellent publication record and expertise in manganese chemistry is essential.

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Computational Quantum Chemistry , California State University, Fullerton

The successful candidate will have completed a Ph.D. in theoretical/computational chemistry and have a record of scholarly accomplishment documented by publications, but a candidate with comparable experience with a productive record in computational chemistry may be considered. The position is for a period of one year and is extendable for an additional six months or more by mutual consent. Teaching one course per semester at the undergraduate level may also be required to prepare the candidate for an academic career in college/university teaching. Because of time constraints, preference will be given to candidates currently residing in the U.S. and with status permitting employment in the U.S.

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Coordination/organometallic chemistry postdoctoral position

We obtained lanthanide compounds with high luminescence quantum yields using multidentate heterocyclic N-donor ligands. This project will involve the synthesis and the photophysical studies of new molecular and supramolecular lanthanide complexes with improved excitation wavelengths, absorption coefficient and quantum yields for application in bioanalysis.

The subject proposed involves the multistep organic synthesis of new ligands and the study of their coordination chemistry with lanthanide ions using different techniques. The structure will be determined by X-ray diffraction studies, NMR, and electrospray studies. The photophysical properties will be investigated in detail, in solution and in the solid states.

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Redox enzyme mechanics and bacterial respiration

Electrochemical investigations of biological processes have provided a wealth of information on the structure-function relationship of redox enzymes, while the underlying technology has formed the basis for biosensors. Biosensors such as the extremely successful glucose biosensor have revolutionised the treatment of diabetes patients around the world and significantly improved their conditions.

In these PhD positions you will use the state-of-the-art in surface physics, colloid and organic chemistry, membrane biology and electrochemistry to develop membrane-modified electrodes with full control of protein-electrode interactions.

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