Postdoctoral position in Synthetic Organic Chemistry: Synthesis of Ferrocenyl-Podophyllo Analogs and their Evaluation as Anti-Tumor Agents

The project will be in collaboration between the team Synthèses Sélectives et Organométalliques (SSO) directed by Prof. G. Poli (Institut Parisien de Chimie Moléculaire, UMR 7201) and the team  Chimie Organométallique Médicinale directed by  Prof. G.  Jaouen at the Ecole Nationale  Supérieure de Chimie de Paris (Laboratoire Charles Friedel, UMR 7223). The Goal is to synthesize a series of ferrocene-containing lignans, such  as  podophyllotoxins.

Among the several existing derivatives of podophyllotoxin, etoposide and teniposide are the only cyclolignans used in cancer chemotherapy so far.  However, these efficient cytotoxic agents  induce severe toxic effects and the discovery of more potent and/or less toxic analogs of this  family would be highly desirable. Accordingly, we aim to develop the synthesis of new ferrocenecontaining cyclolignans and study the pharmacological properties of these original  bioorganometallic targets. This project fully relies on the synergic convergence of the two research groups, that possess complementary skills. From one side, one of the pioneer of bioorganometallic chemistry, having a  longstanding experience in ferrocenyl conjugates and biological tests, from the other side a group  well experienced in multistep organic synthesis, organometallic catalytic synthesis and the  chemistry of lignans.

The successful candidate will be based in the Pr. Poli's team, under the supervision of Dr. J. Oble,  at Université Pierre et Marie Curie, Paris 6, 4 Place Jussieu, 75252 Paris cedex 5. Candidate profil: Experience in multistep synthetic organic chemistry is essential, and applicants must have a PhD  in Synthetic Organic Chemistry.

More Details:
Postdoctoral position in Synthetic Organic Chemistry: Synthesis of Ferrocenyl-Podophyllo Analogs and their Evaluation as Anti-Tumor Agents

Research/Faculty Associate at Gautam Buddha University

Gautam Buddha University invites applications for the post of Research/Faculty Associate in the following areas:

Applied Chemistry (Polymer Chemistry; Green Chemistry; Industrial Chemistry and Medicinal Chemistry, Applied Mathematics, Food Processing & Technology, School of Information and  Communication Technology, Computer Science & Engineering, Electronics & communication Engineering, School of Buddhist Studies & Civilization Buddhist Studies & Civilization, School of Engineering  Civil Engineering, Mechanical Engineering, Electrical Engineering, Architecture & Planning, School of Management

Eligibility and Qualification: Masters degree in relevant discipline with good academic record with minimum 01 year Teaching/Research/Industry experience at appropriate level.

Desirable Qualification:

Ph. D in relevant areas & good research publications.

Terms & Condition:

All appointments are on contractual basis for the period of one academic session.

Reservation policy will be observed.

Salary: Rs. 33,000/- per month (Non Ph. D Candidates) & Rs. 36,000/- per month (Ph. D Candidates)

After preliminary screening the suitable candidate would be called for interview through e-mail, in which the date of interview will be communicated.

Number of post mentioned may vary.

At the time of interview candidates are required to bring their recent passport size photograph, original and Self Attested Photocopy of all documents corroborative of their claims of qualifications and experience. No TA/DA will be given for appearing in the interview. 

More Details:

Research/Faculty Associate at Gautam Buddha University