Highlights:
1. The position is for 2 years to work in the Gough group at the University of Bristol, ranked 32nd in the world according to the QS Top Universities ranking. Although placed in the Computer Science department, the position will involve interacting mostly with the Gough group but also with collaborators at the MRC Laboratory for Molecular Biology in Cambridge, and around the world.
2. The position will include working with data from the SUPERFAMILY database. The initial project is flexible, depending on the candidate, but it must contribute to development of the SUPERFAMILY database and exploit the resource to answer biological questions.
3. We expect this to lead to publications in high profile journals. Many projects in the group relate to evolution, e.g. [Chothia, C. and Gough, J. (2009) Genomic and Structural Aspects of Protein Evolution. Biochem. J. 419(1), 15-28.].
4. Two areas of potential development also include: inclusion of functional information, and automation of the pipeline integrating with SCOP and ASTRAL. The functional work includes automatically adding Gene Ontology but also targetting specific biological processes such as calcium signalling and transcription factors for deeper investigation from a functional and an evolutionary perspective. A candidate may also bring their own research interests to the group.
5. All applicants must possess a PhD, preferrably in: bioinformatics, systems biology, molecular biology or some related subject. Computer skills are essential, in particular bioinformatics and data analysis/manipulation/management skills, e.g. PERL, SQL and Linux. Previous experience of protein sequence analysis is a plus, but not essential. What is important is an interest in molecular biology and some previous experience working with biological data.
6. We kindly ask that applicants explain in their cover letter what interests them about this position, and how their skills and expertise can contribute. We invite applicants both from computational or biological backgrounds, but both must possess computer skills and an interest and basic understanding of molecular biology. We expect all applicants to have a good publication record; this will be one of the most important criteria for selecting candidates for interview.
7. Please apply via E-mail to Julian Gough (gough@cs.bris.ac.uk) including a C.V. with publication list and cover letter. Formal details of the position are available on request.
8. Dr. Julian Gough
Reader, University of Bristol
Department of Computer Science
Merchant Venturers Building
Woodland Road, Bristol, UK
BS8 1UB
Tel: +44 (0)117 3315221
Reference: http://www.cs.bris.ac.uk/~gough/job.html
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