Postdoctoral Fellowship in Computational design of biocatalysts


OCE Postdoctoral Fellowship - Building Biocatalysts by Computational DesignThe Transformational Biology program seeks a postdoctoral candidate to design new biocatalysts in silico. This project will require a large degree of collaboration between several capabilities already present at CSIRO and with international laboratories. The role requires a familiarity with computational algorithms, enzymology and chemistry. The successful candidate will be supported by the enzyme evolution team located at Entomology (Canberra, ACT) and by the structural biology team located at Molecular and Health Technologies (Parkville, Vic) and by the Transformational Biology program. This new technology will be used to develop novel enzymes for a wide range of applications.CSIRO is Australia’s leading research organisation with over 6,500 staff located across the country. Our purpose is to deliver great science and innovative solutions for industry, society and the environment by igniting the creative spirit of our people. The OCE Postdoctoral Fellowship Scheme provides an opportunity to undertake postdoctoral research projects aligned with the best research teams across CSIRO. The ability to create an efficient enzyme catalyst for a chemical reaction of choice has been a long-standing but elusive goal in the field of protein design. In particular, a capability for de novo design of enzymes for which there are no known natural prototypes would have application in many different areas, including biomedicine, green chemistry and renewable energy, and especially biofuels.As part of the Transformational Biology team, the Postdoctoral Fellow will develop the technology to design new enzymes in silico, and these enzymes will then be tested for their functional characteristics and structures. The successful applicant may be required to spend significant time learning software/ techniques in laboratories located in the United States as well.Selection Criteria:Applicants must address the selection criteria. Applicants that do not address the selection criteria will not be considered. To assist you prepare your application please read the information available at "Guidelines for Applicants" on the CSIRO web site.1. A PhD (or will shortly satisfy the requirements for a PhD) in a relevant scientific discipline.2. Experience in computer programming/ algorithm development; more specifically, knowledge of Rosetta software and Monte Carlo methods.3. Knowledge of biology and protein function & structure in particular.4. Demonstrated ability to contribute new ideas to a research project5. Evidence of excellent interpersonal, written and oral communication skills 6. Demonstrated ability to work effectively as part of a team.7. An understanding of the principles and practices of Health Safety and Environment and EEO.Candidates must hold a PhD in a relevant scientific discipline, or will shortly satisfy the requirements for a PhD degree, with no more than three years experience since graduation and must have excellent written, oral and interpersonal communication skills.**CSIRO is strongly committed to Diversity and offers Flexible Working Arrangements and enhanced leave entitlements. Aboriginal and Torres Strait Islanders are encouraged to apply for all CSIRO positions**Note that to be eligible for consideration for appointment to a Post Doctoral fellowship within CSIRO an applicant’s total relevant work experience, on completion of the fellowship at CSIRO, must not exceed six full-time equivalent years since confirmation of their doctorate.**Before you apply ensure that your documents are in Text, MS Word or PDF. Ensure your file is not larger than 1MB in PDF format, or 2MB for all other formats. Your Documents will be converted into PDF format. CSIRO prefers applications be lodged online via this careers site: http://www.csiro.au/resources/Postdoc-Positions.htmlYou are required to include two documents:(1) A document Addressing the "Selection Criteria" and(2) A "Resume or CV" including the names of at least two referees.Note: Applications that do not address the selection criteria will not be considered.If you experience difficulties applying online call 1300 301 509 and someone will be able to assist you. Outside business hours please email: csiro-careers@csiro.auIf you are unable to lodge your application online, please fax your application (quoting reference number 2009/252) to +61 2 6276 6641 or alternatively post to:CSIRO Careers OnlinePO Box 225DICKSON ACT 2602Contact: Should you require more information on this position please contact Tom Peat by email tom.peat@csiro.auPlease do not email your application directly to Tom. Applications received via this method will not be considered. Please use the web site to apply:http://www.csiro.au/resources/Postdoc-Positions.html
Contact:
Tom Peat CSIRO Molecular and Health TechnologiesCSIRO343 Royal ParadeParkville, Victoria 3052AustraliaPhone: +61396627304Fax: +61396627101Email: Send your resume/CV
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Application Deadline: 5/31/2009

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