A PhD position is available on the adaptive potential of molecularresponses to stress, of a freshwater snail exposed to pesticides.Position is opened in the group of Ecotoxicology and quality of aquaticenvironments, UMR ESE 985,
Rennes, of the French National Institute forAgricultural Research (INRA).
The project is proposed in the context of population ecological riskassessment and pesticide use. Evolutionary processes are only recentlyincorporated as a relevant dimension into these research issues. Suchprocesses are difficult to predict, due to the diversity of theirpotential determinants, among which: (i) activated mechanisms ofphysiological and molecular defence, (ii) interactions, (iii)relationship with other traits, including those related to fitness, (iv)potential cost, (v) population characteristics, including history ofexposure, population size and level of genetic variability.Specific issues addressed in this project relate to the components ofvariation observed at the level of biochemical and molecular systemsactivated in response to pesticide stress, in a freshwater snail,/Lymnaea stagnalis/.
We are specifically interested in estimating theadaptive potential of such systems (enzymatic activity, expression ofgenes involved in the antioxidant pathway and in less specific stress)*.The amount of genetic additive variation will be estimated usingquantitative genetics (experimental lines), and adaptive divergencebetween populations will be searched for by comparing contrastedecotypes, using common-garden experiments. Fitness-related traits willbe jointly measured, in order to estimate possible costs and trade-offs.*depending on fundings obtained, the project may be extended to geneexpression at a larger scale (transcriptomics)./
Salary: the project is currently submitted to several national /regional grant sources, including INRA’s “Young Researcher Contract”,which includes both a 3 year PhD funding and a 2 year postdoc funding.
Expected start date is September 2009. If interested, please send(before June 1st ): CV, documentation of undergraduate grades, namesand addresses of two referees and a statement describing the reason(s)for your interest in this research to:
Salary: the project is currently submitted to several national /regional grant sources, including INRA’s “Young Researcher Contract”,which includes both a 3 year PhD funding and a 2 year postdoc funding.
Expected start date is September 2009. If interested, please send(before June 1st ): CV, documentation of undergraduate grades, namesand addresses of two referees and a statement describing the reason(s)for your interest in this research to:
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