Highlights:
- Four year graduate degrees in genomic medicine and statistics
- The 4-year programme will comprise a combined first year and a 3-year self directed research project.
- The first year will include taught modules and laboratory rotations designed to equip students with the knowledge to make an informed choice of doctoral project.
- The programme is available for admission in October 2010 and is open to all Home/EU and overseas students. A starting stipend of approximately £18,685 per annum will be provided. Tuition fees will be paid at the Home/EU rate.
- The deadline for receipt of applications is 14th May 2010.
- Further information on "How to Apply" is available at http://www.medsci.ox.ac.uk/study/graduate/msdtc/4-year-dphil-programs/how-to-apply.
- Enquiries should be directed to enquiries@msdtc.ox.ac.uk
- The
- The programme consists of a one year modular course (including formal teaching and two short research projects) followed by a three year doctoral research project, which can take place in any of the participating departments at the University. The course takes advantage of
- The Wellcome Trust Centre for Human Genetics (WTCHG), which will host the programme, has world-leading groups in statistics, bioinformatics, genomic analysis, protein structure and functional biology. United by a common interest in understanding the molecular basis of disease, researchers are affiliated to diverse departments, with interests ranging from susceptibility to infection, neurodegenerative disorders, cardiovascular disease, language development, mental illness, statistical genetics and statistical bioinformatics, and come from both clinical and pure science backgrounds. This combination of skills and interests, the ability to cross disciplines and to address old problems in new ways, has proved crucial to the scientific success of the WTCHG and provides a unique training opportunity. Students educated within the culture of the WTCHG are encouraged to develop cross-disciplinary interests, and to develop into scientists able to take new and unexpected approaches to old problems using the latest and emerging technologies. The WTCHG is already home to a number of such students and the doctoral programme builds on these, and other, interdepartmental links.
- The doctoral programme is integrated with projects already in place at the WTCHG, identifying the susceptibility genes underlying common disease. Genetic and genomic studies pave the way to answering fundamental questions in epidemiology and disease aetiology: how and why populations differ in their spectrum of disease-variants; how these variants interact with environmental causes; how information about DNA sequence variants, gene expression and protein content relates to disease phenotype; how we can use this flood of new molecular information to arrive at improved definitions of disease that lend themselves to better diagnosis and treatment. Over the next few years it is likely that whole genome systems biology (including DNA copy number detection, gene expression, metabolite profiling and, eventually, whole genome resequencing of very large cohorts) will become routine. Consequently methods and research opportunities for dissecting complex disease will undergo a further revolution. This revolution is likely to be driven by scientists with strong quantitative skills aligned with a deep understanding of the underlying biology.
- Members of the Mathematical Genetics Group at the Department of Statistics at the
Co-Directors:
Jonathan Flint: www.well.ox.ac.uk/flint/
Richard Mott: bioinformatics.well.ox.ac.uk/
Chris Holmes: mathgen.stats.ox.ac.uk/
Peter Donnelly: mathgen.stats.ox.ac.uk/
General Enquiries:
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