Lipidomic Characterization of Body Fluids and Tissues for Patients Suffering from Serious Diseases Using Mass Spectrometry
Postdoc researcher will participate in the development and introduction of new methods in the lipidomic characterization of body fluids and tissues for patients suffering from serious human diseases, such as cardiovascular diseases, various types of cancer or Alzheimer disease. The lipidomic characterization includes all analytical steps starting from the preparation of biological samples (plasma, surgically removed cancer tissues and other types of samples), the preparative fractionation of individual lipid classes and finally detailed characterization using one or multidimensional liquid chromatography coupled to mass spectrometry. The lipidomic quantitation will be performed for large number of lipids followed by the multivariate statistical evaluation (PCA, PLS, etc.) with the goal to find biomarkers for individual types of studied diseases.
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